Profil Indra Wibowo

Indra Wibowo

School of Life Sciences & Technology
Institut Teknologi Bandung
Jl. Ganesa No. 10 Bandung,
Indonesia 40132
Phone: +62 22 251 1575, 250 0258
Fax: +62 22 253 4107
Position : Lecturer/Researcher in Developmental Biology

Academic Career
Lecturer/Researcher in Developmental Biology Institut Teknologi Bandung, Bandung, Indonesia 2010
Doctoraate (Developmental Biology) Centre for Genomic Regulation – Pompeu Fabra University, Barcelona, Spain 2006-2011
Master (Developmental Biology) Wageningen University, Wageningen, The Netherlands 2003-2005
Bachelor (Biology) Institut Teknologi Bandung, Bandung, Indonesia 1997-2001
Employment : Academic Staff (2010 – now)
Research and development projects over the past five years
  1. D evelopmental neurotoxicity of pesticides to aquatic animal . 2013-2014. Funded by Institut Teknologi Bandung.
  2. Zebrafish as a model system to study the expression and physiological function of a novel cannabinoid receptor GPR55 ). 2011-2012. Funded by Indonesia Toray Science Foundation Science and Technology Research Grant
  3. Molecular study of a new cannabinoid receptor GPR55 in zebrafish as a model system. 2011-2012. Funded by Institut Teknologi Bandung.
Reasearch interest
During his master and doctorate studies he had been working with fish, carp and zebrafish, as animal models to investigate several biological phenomena, such as the ones related to immune system and sensory/nervous system as well as tissue regeneration. He is intended to perform biomedical research using zebrafish, especially on the tropical diseases. The current topics that he will develop including small molecules screening from marine algae that have potency in inducing and inhibiting tissue regeneration and also natural product discovery for disease treatments associated with nervous, vascular and immune systems. He will use zebrafish for in vivo study in combination with animal tissue culture for in vitro study.
Work Experiences
October 2006-July 2011 PhD Thesis at the Centre for Genomic Regulation and Pompeu Fabra University, Barcelona, Spain
Title of the thesis: Zebrafish lateral line system: The roles of Eya1 in migrating primordium and Notch signaling in hair cell development and regeneration
June-October 2006 Part-time Job at Biomedical Department, Brawijaya University, Malang, East Java, Indonesia
Project Title: Monoclonal Antibody Production in Humpback Grouper Fish
December 2005-Mei 2006 Post-master projects (research assistant) in Cell Biology and Immunology Department, Wageningen University, The Netherlands
Project Title: Refolding and Purification of Recombinant Carp IL-10 from Bacterial System; and Sequencing and Real Time-PCR Analysis of Complement Genes in Carp
January-August 2005 Thesis projects in Cell Biology and Immunology Department, Wageningen University, The Netherlands
Project Titles: Characterization of carp immune-related genes during parasite infection; and Expression and purification of recombinant carp IL-10
August-December 2004 Internship projects in Hubrecht Laboratory for Developmental Biology, The Netherlands
Project Titles: Genetic linkage mapping of zebrafish BO11CA mutant; and Wnt signaling in zebrafish brain development
Selected Publications and Presentations
Seminar Internasional: The Third International Conference on Bioscience and Biotechnology, Bali, September 21-22, 2011. Oral Presentation .
Real Time PCR Seminar and Workshop: Improving your understanding and data reproducibility. Bandung, 21-22 December 2011Eya1 is essential for Wnt/beta-catenin homeostasis during tissue remodelling (manuscript in preparation) .
Compartmentalized Notch signalling sustains axial references for epithelial planar polarity
Wibowo I , Pinto-Teixeira F, Satou C, Higashijima S, López-Schier H.
Development . 2011 Mar;138(6):1143-52.
Nitric oxide hinders antibody clearance from the surface of Trypanoplasma borreli and increases susceptibility to complement-mediated lysis.
Forlenza M, Nakao M, Wibowo I, Joerink M, Arts JA, Savelkoul HF, Wiegertjes GF.
Mol Immunol . 2009 Oct;46(16):3188-97.
The histone variant macroH2A is an epigenetic regulator of key developmental genes.
Buschbeck M, Uribesalgo I, Wibowo I, Rué P, Martin D, Gutierrez A, Morey L, Guigó R, López-Schier H, Di Croce L.
Nat Struct Mol Biol . 2009 Oct;16(10):1074-9. Epub 2009 Sep 6.
Regeneration of hair cells in zebrafish neuromast. (Poster presented in 2 nd Annual Swiss Zebrafish Meeting, Swisszebra). March 27 th , 2009, Univeristy of Geneva, Switzerland.