![marsel](https://sith.itb.ac.id/wp-content/uploads/sites/386/2017/02/marsel-150x150.jpg)
DR. rer. nat. MARSELINA IRASONIA TAN, MS.
Associate Professor
School of Life Sciences and Technology
Institut Teknologi Bandung, Indonesia
Expertise Group : Animal Physiology, Development, and Biomedical Sciences
Email : marsel@itb.ac.id
Overview
Dr. rer. nat. Marselina Irasonia Tan, MS. focuses in the studies on cellular and molecular biology especially stem cell differentiations, immune system, and cancers, from the processes to strategies to mitigate them. Over the years Dr. Marselina has published multitude of studies related to the human immune systems and their interactions with cancerous cells and tissues to better understand it and improving knowledge in related healthcare sciences and practices. Likewise she has been involved in scientific communities related to medical and stem cell research as well as enlisted as consultants in various pharmaceutical companies in Indonesia.
Bachelor’s Degree
- Universitas Padjajaran, Indonesia (1986). Major: Biology.
Master’s Degree
- Institut Teknologi Bandung, Indonesia (1990). Major: Biology.
Doctoral Degree
- Medical University Lübeck, Germany (1998). Major: Molecular Biology.
Undergraduate Courses
- Immunology, Applied Cellular and Molecular Biology; Animal Development; Animal Cell Culture Engineering
Postgraduate Courses
- Cancer Biology; Biotechnology Research Development, Bioethics, and Patent; Biotechnology Master’s Research; Master’s Thesis Defence; Biomedical Cellular and Tissue Engineering; Infection and Immunity; Advanced Cellular Biology
National Publications :
- Heryakusuma C, Puspasari F, Ihsanawati I, Giri-Rachman EA, Tan MI, Ramadhani E, Nurainy N, Natalia D. 2016. Cloning and Expression of Small Hepatitis B Surface Antigen (sHBsAg) In Hansenula polymorpha . Mikrobiologi Indonesia 10(4)
- Martgrita, M.M., Tan, M.I. (2016) Pengaruh estradiol-17β dan kolagen tipe IV terhadap ekspresi gen PIK3CA untuk menginduksi ekspresi c-erbB2 pada lini sel kanker ovarium SKOV-3. Jurnal Biologi Indonesia 12 (1): 59-66.
- Kurniatanty I, Tan MI, Ruml T, Sumarsono SH. 2015. Potensial cell proliferation inhibitor isolated from Indonesian brown algae (Phaeophyta). International Journal of Pharmacy and Pharmaceutical Sciences 7(11): 140-143. ISSN- 0975-1491
International Publications :
- Winarto H, Tan MI, Sadikin M and Wanandi SI. 2017. ARID1A Expression is Down-Regulated by Oxidative Stress in Endometriosis and Endometriosis-Associated Ovarian Cancer. Translational Oncogenomics 9:1-7.
- Sanawati, A., Barlian, A., and Tan, M. I. Construction, in silico analysis, and in vitro expression of DNA vaccine candidate encoding human rotavirus capsid protein VP6. International Journal of Integrative Biology 18(1): 1-6.
- Rahmah, L., Rachman, E.G., Retnoningrum, D., and Tan, M.I. 2017. Molecular Characterization and Expression of Human Rotavirus Recombinant Protein VP2, VP6, and VP7 Transfected in Vero cell. International Journal of Integrative Biology 18(1): 7-12.
- Tan MI & Hayati 2017. Inhibition of Mammary Gland Cancer Development by Propolis and Mangostin in Female Mice Balb/C. J. Math. Fund. Sci., Vol. XX, No. X, 2017, 49(1): 40-50
- Zachariasova MS, Kurniatanty I, Gbelcovac H, Jirua M, Ruberta J, Nindhiad TGT, D’Acuntoc CW, Sumarsono SH, Tan MI, Hajslova J, and Ruml T. 2017. Bioprospecting of Turbinaria macroalgae as a potential source of health protective compounds. Chemistry & Biodiversity 14(2) (online)
- Herdwiani W, Soemardji AA, El-Fahmi, Tan MI. 2016. Gas Chromatograph spectrometer analysis and acute oral toxicity of Cinnamomum burmannii., Ness Ex.BL. essential oil. Asian Journal of Pharmaceutical and Clinical Research 9(3):240-245
- Herdwiani W, Soemardji AA, El-Fahmi, Tan MI. 2016. A Review of cinnamon as as a potent anticancer drug. Asian Journal of Pharmaceutical and Clinical Research. 9(3):8-13
- Tan, MI. 2016. Cell and molecular biology for diagnostic and therapeutic technology. Journal of Physics: Conference Series 694 (2016) 012001
- Kustiati, Marselina I. Tan, Sri Yusmalinar, Trisnowati B. Ambarningrum and Intan Ahmad. Monitoring Permethrin and Imidacloprid Resistance in Indonesian House Fly Musca domestica L. (Diptera: Muscidae). Journal of Entomology 2016: 13 (1-2): 40-47
- Ugiyadi, M., Tan , M. I., Giri-Rachman, E. A., Zuhairi, F.R., and Sumarsono S. H.. 2013. The expression of essential components for human influenza virus internalisation in Vero and MDCK cells. Cytobiotech, Published online: 04 August 2013.
- Zuhairi, F.R.,, Ugiyadi, and M., Tan , M. I. . 2012. The role of trypsin in the internalization process of influenza H1N1 virus into Vero and MDCK Cells. ITB Journal of Science , 4A: 297-307
- Rahayu, R., Ahmad, I., Ratna E.S., Tan, M.I ., and Hariani, N. 2012. Present status for carbamate, pyrethroids and phenylpyrazole insecticide resistance to German cockroach, Blatella germanica in Indonesia. Journal of Entomology , 9: 361-367.
- Tan, M.I. 2003. Effect of Sargassum Siliquosum extract on the expression of p53 and estrogen receptor on Breast Cancer Cell Line T47D and MCF7. Proceedings of International on Biomedicines 114-122
Proceeding:
- Martgrita, M.M., Tan, M.I. (2015) The Role of Estradiol-17β and Type IV Collagen on the Regulation and Expression Level of c-Erbb2 RNA and Protein in SKOV-3 Ovarian Cancer Cell Line. XIII International Conference on Cancer Science and Therapy (ICCST 2015), Singapore; eISSN: 1307-6892.
- Martgrita, M.M., Gunarta, I K., Tan, M.I. (2015) The Role of Estradiol-17β and Type IV Collagen on GPR55 Gene Expression that Contributed to Increase SKOV-3 Ovarian Cancer Cell Line Proliferation. International Conference on Biological, Civil and Environmental Engineering (BCEE-2015), Denpasar, Bali; ISBN: 978-93-84422-08-0.
International Seminars :
- Sanawati, A., Barlian, A., dan Tan, M. I. (2016): Preparation and caharcterization of a rotavirus DNA vaccine encapsulated in chitosan nanoparticles, International Seminar and Workshop on Nanobiotechnology, Bandung-Indonesia.
- Rahmah, L., Rachman, E.G., Retnoningrum, D., dan Tan, M.I. (2016): Expression and Characterization of VP2, VP6, and VP7 Rotavirus protein in mammalian cell, Asean Microbial Biotechnology Conferences, Bali-Indonesia.
- Tan, MI. BRD4 and NF-κB pathway in ovarian cancer cells. FK-UNPAD, The 4th. Bandung international Biomolecular Medicine Conference. 5-6 September 2016. Bandung, Indonesia
- Tan, MI. Identifying Challenges of Biosimilar Drug Development. Bioprocess & Technology and 2016. APAC Summit IBC Asia, Singapore
- Tan, MI. Brd4 function on NFkappaB pathway.The 6th Annual Basic Science International Conference. 2-3 Maret 2016. Malang Indonesia
- Tan, MI & F Roesl. 2016. Effect of oxidative stress (hypoxia) on important cytokine in innate immune response on E6, E7, E6/E7- HPV16- human immortalized keratinocytes cells. AMBC, Bali, Indonesia
- Martgrita, M.M., Tan, M.I. (2015) XIII International Conference on Cancer Science and Therapy (ICCST 2015) The Role of Estradiol-17β and Type IV Collagen on the Regulation and Expression Level of c-Erbb2 RNA and Protein in SKOV-3 Ovarian Cancer Cell Line. Singapore, 2015
- Isma Kurniatanty, Sony Heru Sumarsono & Marselina I.Tan . 2013. Preliminary study of anticancer activity from brown algae (Phaeophyta) extracts. International Seminar on Tropical Bioresources for Sustainable Bioindustry. ITB Bandung, 30–31 October 2013
- Maharani Ugayadi, Marselina I Tan , Ernawati A Giri rahman, Fawzi R Zuhairi, Sony H Sumarsono. Primary monkey trachea cell culture express the subtantial components for influenza virus internalization. International Seminar on Tropical Bioresources for Sustainable Bioindustry. ITB Bandung, 30–31 October 2013
National Seminar :
- Sanawati, A., Barlian, A., dan Tan, M. I. (2016): Kloning dan karakterisasi in silico gen VP6 dari rotavirus G1P[8], Seminar Nasional Biologi USU, Medan-Indonesia.
- Rahmah, L., Rachman, E.G., Retnoningrum, D., dan Tan, M.I. (2016): Kloning dan Karakterisasi Molekular Gen VP2 dan VP7 dari Rotavirus RV4 (G1P[8], Seminar Nasional Biologi USU, Medan-Indonesia.
Books
- Marselina I. Tan & Anggraini Barlian & Ernawati GR : BIOLOGI SEL DAN TERAPANNYA. Penerbit ITB 2015
- Marselina I. Tan. Karsinogenesis oleh Bahan Kimia. Basic Science of Oncology-Ilmu Onkologi Dasar. Perhimpunan Onkologi Indonesia 2010
- Marselina I. Tan. Hormon dan enzim pada kanker. Basic Science of Oncology-Ilmu Onkologi Dasar. Perhimpunan Onkologi Indonesia 2010
- Marselina I. Tan. Onkogen. Basic Science of Oncology-Ilmu Onkologi Dasar. Perhimpunan Onkologi Indonesia 2010
Patent:
- Anggota dalam Tim. Kit Diagnostik Untuk Mendeteksi Infeksi Virus Hepatitis B Menggunakan Antibodi Primer lgY Anti Hepatitis B Surface Antigen (HBsAg) dan Antibodi Sekunder Monoklonal Anti-HBsAG Yang Terkonjugasi Horseradish Peroxidase (HRP) dan Proses Pembuatannya. 2018. P00201800256
- Society for Medicinal Plant Research – Gesellschaft fuer Arzneiplanzenforschung
- Asosiasi Sel Punca Indonesia (Indonesian stem cell association)
- Perhimpunan Ahli Anatomi Indonesia (Indonesian anatomy experts association)
Grants Awarded as Principal Investigator
- Sistem Pencitraan Gelombang Mikro Untuk Deteksi Dini Kanker Payudara: Proof-Of-Concept & Phantom Validation. RISET ITB. 2018
- Sistem analisis pengenalan gambar kromosom pada darah. Penelitian Terapan Unggulan Perguruan Tinggi-Riset DIKTI. 2018
- Produksi HBsAg dan Anti-HBsAg Untuk Pengembangan serta Komersialisasi Kit Diagnostik Hepatitis B Indonesia. Rispro LPDP. 2016-SEKARANG
- Pengembangan dan pengujian efek antikanker nanopartikel BRD4-inhibitor-jakalin-kitosan secara in vitro pada lini sel kanker ovarium dan payudara Riset dan Inovasi KK-ITB 2016/2017
- Analisa Profil Exosome pada Urine dan Darah penderita prediabetes di sekitar Bandung sebagai Upaya Identifikasi Kandidat Biomarker Prediabetes Nutrifood Research Grant 2016
- Produksi conditioned medium sel punca mesenkim (human adipose tissue derived mesenchymal stem cells-conditioned medium) sebagai bahan antiaging: Pembuatan karyotyping stem cell. Program Insentif Riset Sistem Inovasi Nasional 2016