Sekolah Ilmu dan Teknologi Hayati - Institut Teknologi Bandung

Enter your keyword

Ernawati Arifin Giri-Rachman, Ph.D.

  • Home
  • Ernawati Arifin Giri-Rachman, Ph.D.

Ernawati Arifin Giri-Rachman, Ph.D.

Asisten Profesor
Genetika dan Bioteknologi Molekuler
Sekolah ilmu dan teknologi hayati
Institut teknologi bandung
Email : erna_girirachman@itb.ac.id
SINTA | Google Scholar | Scopus

RINGKASAN

Ernawati Giri-Rachman, Ph.D. merupakan salah satu dosen pada kelompok keahlian genetika dan bioteknologi molekuler yang fokus pada bidang mikrobiologi molekuler, virologi, biologi molekuler dan sel. Dr Ernawati juga aktif dalam beberapa proyek baik di dalam maupun luar negeri, seperti proyek pengembangan vaksin covid-19 dan hepatitis B. Dr, Ernawati merupakan Ketua Satgas Covid-19 ITB dan tergabung dalam tim penanganan Covid-19 dan percepatan vaksin di kancah pemerintahan daerah dan nasional. Dr Ernawati adalah anggota aktif di beberapa organisasi nasional dan internasional yang berkaitan dengan virologi, mikrobiologi dan biologi molekuler.

Pendidikan

Bachelor’s degree

  • Institut Teknologi Bandung, Indonesia (1993). Bidang Utama : Kimia

Master’s degree

  • Institut Teknologi Bandung, Indonesia (1997). Bidang Utama : Kimia

Doctoral degree

  • University of Bristol (2003). Major field : Molecular Microbiology

Publikasi dan HAKI

Contribution to GenBank NCBI Database

  • Efendi,Y.S., Susanti,D., Tritama,E., Putri,G.N.N., Raharso,S.,Iskandar,I., Aditiawati,P., Giri-Rachman,E.A., Mukhopadhyay,B. and Purwantini,E. Bordetella pertussis strain Pelita III, complete genome. GenBank : NZ_CP019957. 2017
  • Giri-Rachman,E.A ., Kocher,J.F., Li,G., Bui,T., Jiang,X. and Yuan,L. Norovirus Hu/GII.4 2006b/092895/2008/USA major capsid protein gene, complete cds.GenBank: KC990829.1. 2013
  • Jinata,C., Giri-Rachman,E.A . and Retnoningrum,D.S. Hepatitis B virus isolate CJ66 small S protein (sHBsAg) gene, partial cds. JQ646056.1-JQ646072, 2012 (18 sequences)

Journal

  • Naully, P. G., Tan, M. I., Agustiningsih, A., Sukowati, C., & Giri-Rachman, E. A. (2024). cccDNA epigenetic regulator as target for therapeutical vaccine development against hepatitis B. Annals of hepatology, 30(1), 101533. Advance online publication. https://doi.org/10.1016/j.aohep.2024.101533
  • Giri-Rachman, E. A., Tan, M. I., Intan, N. N. S., Fajar, N. P. A., Wojciechowska, G. E. P., Hertadi, R., & Retnoningrum, D. S. (2024). In Silico Study, design, and expression of an intranasal dual chimeric vaccine for Indonesian-Based norovirus GII-2 and hepatitis B. HAYATI Journal of Biosciences, 31(5), 1007–1018. https://doi.org/10.4308/hjb.31.5.1007-1018
  • Giri-Rachman, E. A., Effendy, V. V., Azmi, M. H. S., Yamahoki, N., Stephanie, R., Agustiyanti, D. F., Wisnuwardhani, P. H., Angelina, M., Rubiyana, Y., Aditama, R., Ningrum, R. A., Wardiana, A., & Fibriani, A. (2024). The SARS-CoV-2 Mpro Dimer-Based Screening System: A Synthetic Biology Tool for Identifying Compounds with Dimerization Inhibitory Potential. ACS Synthetic Biology, 13(2), 509–520. https://doi.org/10.1021/acssynbio.3c00446
  • Naully, P. G., Tan, M. I., Nugrahapraja, H., Artarini, A. A., Aditama, R., & Giri-Rachman, E. A. (2024). Design of multi-epitope-based therapeutic vaccine candidates from HBc and HBx proteins of hepatitis B virus using reverse vaccinology and immunoinformatics approaches. PLoS ONE, 19(12), e0313269. https://doi.org/10.1371/journal.pone.0313269
  • Agustini, D. M., Hermawati, E., Giri-Rachman, E. A., Happyana, N., & Juliawaty, L. D. (2024). Synthesis and biological activity evaluation of two derivatives of 7-Aminocephalosporanic acid. Chemistry Africa, 7(6), 3119–3127. https://doi.org/10.1007/s42250-024-01010-4
  • Anindyajati, N., Afifah, S. A., Riani, C., Tan, M. I., Natalia, D., Giri-Rachman, E. A., & Artarini, A. (2024). Improvement of Plasmid Volumetric Yield by Addition of Glycerol and Phosphate Buffer in Escherichia coli TOP10 Batch Culture. HAYATI Journal of Biosciences, 31(3), 572–580. https://doi.org/10.4308/hjb.31.3.572-580
  • Steven, N., Aditama, R., Alifia, A., Hermawati, E., Bachtiar, E., Rahmita, M., Fibriani, A., Syah, Y. M., & Giri-Rachman, E. A. (2024). Development of a dimer‐based screening system that targets PhoR, a sensor kinase of the two‐component regulatory system, in Mycobacterium tuberculosis. Indonesian Journal of Biotechnology, 29(3), 160. https://doi.org/10.22146/ijbiotech.89602
  • Steven, N., Aditama, R., Alifia, A., Hermawati, E., Bachtiar, E., Rahmita, M., Fibriani, A., Syah, Y. M., & Giri-Rachman, E. A. (2024). Development of a dimer‐based screening system that targets PhoR, a sensor kinase of the two‐component regulatory system, in Mycobacterium tuberculosis. Indonesian Journal of Biotechnology, 29(3), 160. https://doi.org/10.22146/ijbiotech.89602
  • Artarini, A., Hadianti, T., Giri-Rachman, E. A., Tan, M. I., Safitri, I. A., Hidayat, N. A., Retnoningrum, D. S., & Natalia, D. (2023). Development of Adenovirus-Based COVID-19 vaccine candidate in Indonesia. Molecular Biotechnology. https://doi.org/10.1007/s12033-023-00749-4
  • Suryohastari, R. R. B., Sumarsono, S. H., Giri-Rachman, E. A., Edi, S. P., Sukoco, R., & Wicaksana, D. N. (2024). Microbial Count and AvBD10 Expressions in Ovaries and Oviducts of Kampung Unggul Balitbangtan (KUB)-1 Chickens Following Intravaginally CpG-ODN and <i>S</i>. Enteritidis. Journal of Tropical Biodiversity and Biotechnology, 9(2), 88750. https://doi.org/10.22146/jtbb.88750
  • Rizarullah, N., Aditama, R., Giri-Rachman, E. A., & Hertadi, R. (2024). Designing a Novel Multiepitope Vaccine from the Human Papilloma Virus E1 and E2 Proteins for Indonesia with Immunoinformatics and Molecular Dynamics Approaches. ACS Omega, 9(14), 16547–16562. https://doi.org/10.1021/acsomega.4c00425
  • Tafroji, W., Bernadette, F.M., Giri Rachman, E.A., Safari, D. 2020. The use of PCR and BsmAI restriction combination targeting wciP gene to determine serotype 6A, 6B, 6C and 6D Streptococcus pneumoniae. Journal of Microbiological Methods. Vol. 172
  • Almando Geraldi, Ernawati A. Giri-Rachman. 2018. Synthetic biology-based portable in vitro diagnostic platforms Alexandria journal of medicine, 54 (4), 423-428.
  • Yusuf Efendi, Dwi Susanti, Erman Tritama, Michelle Pasier, Gilang Putri, Sugeng Raharso, Iskandar Iskandar, Pingkan Aditiawati, Ernawati Giri-Rachman, Biswarup Mukhopadhyay, and Endang Purwantini. 2017. Complete genome sequence of Bordetella pertussis Pelita III, the production strain for an Indonesian Whole Cell Pertussis Vaccine. Accepted in Genome Announcements.
  • Latri Rahmah, Ernawati G Rachman, Debbie S. Retnonigrum, Marselina I. Tan. 2017. Molecular characterization and expression of human Rotavirus Recombinant Protein VP2, VP6 and VP7 transfected in Vero Cell. International Journal of Integrative Biology. 18:1
  • Lei S, Ramesh A, Twitchell E, Wen K, Bui T, Weiss M, Yang X, Kocher J, Li G, Giri-Rachman E, Trang NV, Jiang X, Ryan EP, Yuan L. 2016. High Protective Efficacy of Probiotics and Rice Bran against Human Norovirus Infection and Diarrhea in Gnotobiotic Pigs. Front Microbiol. 2016, 7:1699
  • CHRISTIAN HERYAKUSUMA, FERNITA PUSPASARI, IHSANAWATI IHSANAWATI, ERNAWATI ARIFIN GIRI-RACHMAN, MARSELINA IRASONIA TAN, EKAPUTRA RAMADHANI, NENI NURAINY, DESSY NATALIA. Cloning and Expression of Small Hepatitis B Surface Antigen (sHBsAg) In Hansenula polymorpha. Mikrobiologi Indonesia. 2016.
  • Wang H, Gao K, Wen K, Allen IC, Li G, Zhang W, Kocher J, Yang X, Giri-Rachman E, Li GH, Clark-Deener S, Yuan L. 2016. Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with human gut microbiota. [full text]. BMC Microbiol. 16(1):109. doi: 10.1186/s12866-016-0727-2
  • Ernawati Arifin Giri-Rachman, Indah Woro Utami, Shinta Kusumawardani, Debbie Soefie Retnoningrum, Dessy Natalia, Nurfitriani, Gilang Nadia, Patricia Gita Naully and Neni Nurainy. 2015. Construction, Expression and Characterization of Multi Cassettes Encoding Indonesian Small Hepatitis B Surface Antigen (s-HBsAg) in Methylotropic Yeast Pichia pastoris. Biotechnology 14(5): 225-232 DOI: 10.3923/biotech.2015.225.232
  • Ernawati Arifin Giri-Rachman,Fenryco Pratama, Oktira Roka Aji, Arum Patriati, Ihsanawati, Maelita Ramdani Moeis, Edy Giri-Rachman Putra. 2015. Expressionand Purification of PhoR SensorDomain Histidine Kinaseof Mycobacterium tuberculosisin Eschericia coli. Submited to Microbiology Indonesia, under review.
  • ERNAWATI ARIFIN GIRI-RACHMAN M.Si, Ph.D, Dr. IHSANAWATI S.Si., MAELITA RAMDANI, FENRYCO PRATAMA, OKTIRA ROKAAJI, ARUM PATRIATI, EDY GIRI RACHMAN PUTRA. Expression and Purification of PhoR Sensor-Domain Histidine Kinase of Mycobacterium tuberculosis in Escherichia coli. JURNAL MIKROBIOLOGI INDONESIA. 2015.
  • Zhang H, Wang H, Shepherd M, Wen K, Li G, Yang X, Kocher J, Giri-Rachman E, Dickerman A, Settlage R, Yuan L. 2014. Probiotics and virulent human rotavirus modulate the transplanted human gut microbiota in gnotobiotic pigs. Gut Pathog. 2014 Sep 9;6:39. doi: 10.1186/s13099-014-0039-8.
  • Oktira Roka Aji, Dyshelly Nurkartika Pascapurnama, Fenryco Pratama, Ihsanawati Ihsanawati, Maelita Ramdhani Moeis, Ernawati Arifin Giri-Rachman, 2014. Cloning, Overexpression, and Purification of PhoR CytoplasmicDomain Protein from Mycobacterium tuberculosis strain H37Rv. Vol 8, No 4 (2014)
  • Jacob Kocher, Tammy Bui, Erna Giri-Rachman, Ke Wen, Guohua Li, Xingdong Yang,Fangning Liu, Ming Tan, Ming Xia, WeimingZhong, Xi Jiang, and Lijuan Yuan. 2014. Intranasal P particle vaccine protects against human GII.4 norovorus infection and diarrhea in gnotobiotic pigs. J Virol. pii: JVI.01249-14.
  • Ke Wen, Christine Tin, Haifeng Wang, Xingdong Yang,Guohua Li, Ernawati Giri-Rachman , Jacob Kocher, Tammy Bui, Sherrie Clark-Deener, Lijuan Yuan. 2014.Probiotic Lactobacillus rhamnosusGG enhanced Th1 cellular immunity but did not affect antibody responses in a human gut microbiota transplanted neonatal gnotobiotic pig model. [full text]. PLoS One. 10;9(4):e94504. doi: 10.1371 Husen Zhang, Haifeng Wang, Megan Shepherd, Ke Wen, Guohua Li, Xingdong Yang, Jacob Kocher,Ernawati Giri-Rachman , Allan Dickerman, Robert Settlage, Lijuan Yuan. Lactobacillus rhamnosusGG modulates the human gut microbiota in rotavirus vaccinated and challenged gnotobiotic pigs. 2013. Submitted
  • Ugiyadi M, Tan MI, Giri-Rachman EA, Zuhairi FR, Sumarsono SH. The expression of essential components for human influenza virus internalisation in Vero and MDCK cells. Cytotechnology . Published online 2013 Aug 4
  • Martius E., Mardjuki A, Giri-Rachman, E , Riani C, Cahyati , Retnoningrum DS. 2013. Role of Lys59 and Lys386 of streptokinase from type 12 group A Streptococcus on in vitro stability against plasmin cleavage. Journal of Pure and Applied Microbiology , 7: 2617-2627
  • Chandra Jinata,Ernawati Arifin Giri-Rachman and Debbie Soefie Retnoningrum. 2012. Molecular Analysis of Immune Escape Mutants of Hepatitis B Virus from Local Clinical Samples. Microbiology Indonesia. 6 (1), 9-14.
  • FX Reymond Sutandy, Putri Dwi Utari, Tati Kristianti, Sony Suhandono, Amy Estiati and Ernawati A. Giri Rachman. 2012. Transformation and Analysis of L-HBsAg DNA Transient Expression in Tobacco (Nicotiana tabacum Linn.) Seedlings.Journal of Life Sciences and Technology (STM online Journal) School of Life Science and Technology, ITB, 1 (1) : 19-24
  • Aldina S. Suwanto, Ihsanawati and Ernawati Arifin Giri-Rachman. 2011. Molecular Cloning of PhoR Sensor Domain from Mycobacterium tuberculosis for Structure-Based Discovery of Novel AntiTubercular Drugs . Journal of Life Sciences . 5:454-459
  • Zrimi, J., A. N. Ling, A. Giri-Rachman, G. Feverati, C. Lesieur., 2010. Cholera Toxin B Subunits Assemble into Pentamers – Proposition of a Fly-Casting Mechanism. Plos One 5 (12) e15347 (eISSN-1932-6203)
  • Sony Suhandono, Rasi Fitria, Ernawati Arifin Giri Rachman. 2010. Sequence Analysis of PutativepotB , potC , and potD Genes from Serratia rubidae . Microbiology Indonesia . 4:2, (ISSN 1978-3477)
  • Patrisia Puspapriyanti, Johan Lucianus, Ernawati A. Giri-Rachman . 2010. Kloning DNA Pengkode PhoQ untuk Pengembangan High Throughput Screening System sebagai Usaha Mencari Antibakteri Baru terhadap Salmonella typhi. Jurnal Kedokteran Maranatha . 9(2): 136-145 (ISSN 1411-9641)
  • Kirby Saputra, Johan Lucianus, Ernawati A. Giri-Rachman. 2010. Deteksi mutasi pada Quinolone Resistance Determining Region (QRDRs) gen gyrA pada Salmonella typhi Isolat Klinik dan Galur khas Indonesia. Jurnal Kedokteran Maranatha 9(1): 1-7 (ISSN 1411-9641)
  • Suhandono S., Giri-Rachman E. A. , I.M Zainuddin, P D Utari, A. Supraba and A. Estiati. 2007. Construction of Binary Vector with Wound Inducible Promoter For HBsAg Expression : Development of Plant–based Edible Hepatitis B Vaccine from Indonesian isolate. Annales Bogorienses 11 (1): 8-18 (ISSN : 0517-8452).
  • Ernawati Arifin Giri-Rachman and Fernita Puspasari “Study of D51 mutant of Cpx two component regulatory system in Vibrio cholerae”, ITSF Seminar, February 2005
  • Ernawati Arifin Giri-Rachman, Lolke de-Haan, Claire Lesieur, Fernita Puspasari and Timothy R.Hirst, “The role of Cpx two component regulatory system in Vibrio cholerae”, International Biotechnology Conference, Bali, December 2004.
  • Ernawati Arifin Giri-Rachman, Lolke de-Haan, Kurshid Nurmahomed, Timothy R.Hirst “Cpx dan pengendalian faktor virulensi di Vibrio cholerae”, PIT PERMI, 2003.
  • Ernawati Arifin Giri-Rachman, Lolke de-Haan, Claire Lesieur, Timothy R.Hirst” Cpx two component regulatory system di Vibrio cholerae”, Seminar Jurusan Kimia ITB, 2003
  • Ernawati Arifin Giri-Rachman, “The Cpx two component regulatory system of Vibrio cholerae”. PhD Thesis, 2003.
  • Ernawati Arifin Giri-Rachman dan Timothy R.Hirst, “The Cpx two component regulatory system in Vibrio cholerae”. Bristol Microbiology Forum, University of Bristol, UK, 2002.
  • Ernawati Arifin Giri-Rachman, Kurshid Nurmahomed, Mark Toleman and Timothy R. Hirst,”The Cpx two component regulatory system in Vibrio cholerae”, Society of General Microbiology, University of Worrick, 2002.

Patents

  • KIT DIAGNOSTIK UNTUK MENGKUANTIFIKASI INFEKSI VIRUS HEPATITIS B BERDASARKAN KENAIKAN LAJU ABSORBANSI ENZYME-LINKED IMMUNOSORBENT ASSAY Inventor : Ernawati Arifin Giri-Rachman, M.Si., Ph.D., Prof. Dr.rer.nat. Marselina Irasonia Tan, M.S., Wardono Niloperbowo, Ph.D., apt. Anindyajati, S.Farm., M.Si., Jessica Laurelia, Hafiza Rahmadini, Khairunnisa Nomor Permohonan : S00202401183
  • KIT UNTUK PENAPISAN SENYAWA KANDIDAT OBAT ANTIVIRUS BERTARGET DOMAIN C-TERMINAL PROTEIN NUKLEOKAPSID SARS-COV-2 Nomor Permohonan : P00202309089
  • PLASMID VEKTOR EKSPRESI VAKSIN MULTIEPITOPE SARS-CoV-2 DENGAN KEMAMPUAN UNTUK MENGAMPLIFIKASI DIRI DI DALAM SEL INANG Nomor Permohonan : P00202210964
  • PLASMID VEKTOR EKSPRESI REKOMBINAN UNTUK PENAPISAN CEPAT KANDIDAT OBAT ANTI-SARS-COV-2 YANG MENARGET SISI DIMERISASI DARI PROTOMER MAIN PROTEASE SARS-COV-2 Nomor Permohonan : P00202110062
  • PRODUK BAKTERI Escherichia coli YANG DIMODIFIKASI DAN METODE UNTUK MEMPRODUKSI ENZIM PROTEASE HIV (HUMAN IMMUNODEFICIENCY VIRUS) DALAM TINGKAT EKSPRESI YANG OPTIMUM MENGGUNAKAN PRODUK BAKTERI TERSEBUT Nomor Permohonan : P00202000551

Book

  • Marselina Irasonia Tan, Anggraini Barlian, Ernawati A. Giri-Rachman, Biologi Sel dan Terapannya. Penerbit ITB. 2015

Proceeding

  • Feraliana, Nathanael Steven, Mellysa Rahmita, Ernawati Giri Rachman, Azzania Fibriani. 2017. Development of the high throughput system for screening novel HIV drugs from Indonesian natural resources. The 9th International seminar of indonesian microbiology (ISISM 9). PERMI Palembang. Palembang-Indonesia
  • Feraliana, Nathanael Steven, Mellysa Rahmita, Ernawati Giri Rachman, Azzania Fibriani. 2017. Development of the high throughput system for screening novel HIV drugs from Indonesian natural resources. The 9th International seminar of indonesian microbiology (ISISM 9). PERMI Palembang. Palembang-Indonesia
  • Langi, Gladys Emmanuella Putri ; Moeis, Maelita R. ; Ihsanawati, Giri-Rachman, Ernawati Arifin , Molecular cloning and cold shock induced overexpression of the DNA encoding phor sensor domain from Mycobacterium tuberculosis as a target molecule for novel antitubercular drugs, AIP Conference Proceedings, Volume 1589, Issue 1, p.407-410
  • Dina Rachmi Ramdhani, Putri Dwi Utari, Ima Mulyama Zainuddin, Ami Estiati, Sony Suhandono,Ernawati A. Giri-Rachman. 2009. Construct DNA Encoded Large Hepatitis B Surface Antigens (L-HBsAg) from Indonesian Isolates into Expression of Vector pCAMBIA 1390 to Development of The Third Generation Vaccine. Proceeding of International Conference and Exhibition on Biomass Production , School of Life Sciences and Technology, ITB. ISBN 978-60296488-0-5
  • Ima Mulyama Zainuddin , Sony Suhandono, Ernawati Arifin Giri-Rachman , Ami Estiyati . 2007. “Construction of Binary Vector with MeEF1 Promoter for Gene Expression of Hepatitis B SurfaceAntigen (HBsAg) in Plant.” Proceeding in International Seminar on Pharmaceutics. School of Pharmacy Institut Teknologi Bandung.
  • Saripah Sundari, Junessa Palao, and Ernawati Giri-Rachman . Targetting PhoP-PhoR two component signal transduction to develop a novel high throughput screening system for searching new antibacterial against M . tuberculosis. Proceeding of International Conference and Exhibition on Biomass Production , School of Life Sciences and Technology, ITB . ISBN 978-602-96488-0-5
  • Mufti Hatur Rahmah and Ernawati A. Giri-Rachman . 2009. Amplification of truncated MprB encoding gene to Develop a Novel High ThroughputScreening System for Searching New Antibacterial against Mycobacterium Tuberculosis. Proceeding of International Conference and Exhibition on Biomass Production, School of Life Sciences and Technology . ISBN 978-602-96488-0-5
  • Ima Mulyama Zainuddin, Ima, Sony Suhandono, Ernawati A. Giri-Rachman , Amy Estiati.2008. Isolation of Poly-A vspB Fragment from Soybean cv. Slamet, Proceeding in International Conference of Mathematical and Natural Sciences
  • Ernawati Arifin Giri-Rachman , Thomas Robertus and Sarwono Hadi. 2006. “PCR for detectionSalmonella typhi strain Ind onesia.” Proceeding in International Conference of Mathematical and Natural Sciences.

Pengabdian Kepada Masyarakat

Tahun Nama Kegiatan Leader Personil
2023 MOLECULAR PHYLOGENETIC ANALYSIS AND DNA BARCODE [SITH.PPMI-2-07-2023] Dadang Sumardi  Fenny Martha Dwivany; Adi Pancoro; Sony Suhandono; Husna Nugrahapraja; Azzania Fibriani; Ernawati Arifin Giri-rachman; Karlia Meitha; Popi Septiani;
2024 MENGGALI POTENSI SUMBERDAYA GENETIK PADI LOKAL MELALUI PEMULIAAN PARTISIPATIF DI KECAMATAN TANJUNGSARI KABUPATEN SUMEDANG [SITH.PPMI-2-11-2024] Popi Septiani  Dadang Sumardi; Husna Nugrahapraja; Azzania Fibriani; Ernawati Arifin Giri-rachman; Sony Suhandono; Adi Pancoro; Karlia Meitha; Fenny Martha Dwivany;
2024 DAPT-EQUITY2024@PENETRASI PASAR PENELITI UNTUK PRODUK KIT DIAGNOSTIK HEPATITIS B KUANTITATIF HEPASONA [LPIK1.PM-8-05-2024] Ernawati Arifin Giri-rachman 

Riset

Pendanaan

Tahun Judul Penelitian
2020 Studi Ketahanan Pada Populasi orang Indonesia yang terdedah infeksi Corona Virus Disease (COVID)-19 di Wuhan, Cina
2021 PRAKTIKUM MATA KULIAH PROGRAM STUDI
2022 Identifikasi Dan Karakterisasi Senyawa Metabolit Dari Tanaman Lokal Indonesia Untuk Kandidat Senyawa Antimikroba Dan Antivirus Menggunakan Pendekatan Bioinformatika
2023 Evaluasi imunologi kandidat vaksin multivalen glikokonjugat untuk pencegahan infeksi Campylobacter jejuni dan Flu burung di ayam
2023 Molecular Phylogenetic Analysis and DNA Barcode (PM)
2023 Pengembangan Kit Diagnostik Berbasis Elisa Kuantitatif untuk Pemantau Infeksi Hepatitis B Kronis
2023 Studi Biodiversitas Molekuler Mikroba Danau Halofilik Gili Meno Lombok
2023 RIIM GELOMBANG III – PENGEMBANGAN TEKNOLOGI BIOPROSES UNTUK PRODUKSI MRNA SPIKE-SARS- COV-2 YANG STABIL UNTUK MENUNJANG HILIRISASI DAN KEMANDIRIAN VAKSIN DI INDONESIARIIM GELOMBANG III – PENGEMBANGAN TEKNOLOGI BIOPROSES UNTUK PRODUKSI MRNA SPIKE-SARS- COV
2024 DAPT-Equity2024@Penetrasi Pasar Peneliti untuk Produk Kit Diagnostik Hepatitis B Kuantitatif Hepasona
2024 Desain dan Modifikasi mRNA untuk Efisiensi Produksi Kandidat Vaksin Terapi Hepatitis B bertarget Epigenetik
2024 Pengembangan Kandidat Vaksin mRNA Berbasis Manipulasi Epigenetik cccDNA Untuk Terapi Hepatitis B Kronis
2024 Praktikum Mata Kuliah Biological Threat Agent and Risk Analysis of Biological Hazard Mahasiswa Prodi Intelejen Medik
2024 Studi Biodiversitas Danau Gili Meno – Lombok dengan pendekatan Genomik
2020-2021 PENDANAAN RISET INOVATIF PRODUKTIF (RISPRO) KOMPETISI TAHUN KETIGA BERJUDUL PRODUKSI HBSAG DAN ANTI HBSAG UNTUK PENGEMBANGAN SERTA KOMERSIALISASI KIT DIAGNOSTIK HEPATITIS B INDONESIA
2022-2023 PRAKTIKUM MATA KULIAH PROGRAM STUDIINTELIJEN MEDIK
2023-2024 RIIM Gelombang III – Pengembangan Teknologi Bioproses untuk Produksi Mrna Spike-SARS- CoV-2 yang Stabil untuk Menunjang Hilirisasi dan Kemandirian Vaksin di Indonesia
2024 STUDI IMUNOLOGI DARI KANDIDAT VAKSIN TERAPI BERBASIS MULTIEPITOP BARU TERHADAP HUMAN PAPILLOMA VIRUS DI INDONESIA
2024 SKRINING KETAHANAN TERHADAP CEKAMAN KEKERINGAN PADA PADI LOKAL
2025 OPTIMASI PROSES TRANSKRIPSI IN VITRO DAN UJI EKSPRESI KANDIDAT VAKSIN MRNA MULTI-EPITOP HBC DAN HBX UNTUK TERAPI HEPATITIS B KRONIK

Proyek Penelitian dan Pengembangan

  • Studi Ketahanan Pada Populasi Orang Indonesia yang Terdedah Covid-19. Kemenristek DIKTI. Ketua. 2020
  • Produksi Kandidat Vaksin Covid-19 dengan Platform Vektor Adenovirus. Yayasan Solidarity Forever. Anggota. 2020
  • Komersialisasi Kit Hepatitis B Kualitatif Berbasis ELISA. Kemenristek Dikti, Science Technology Park, ITB. Ketua. 2019
  • The Development of Intranasal Vaccine for Hepatitis B and Norovirus CRDF Global (US grant, collaboration with Virginia Tech, US). Ketua. 2018-2019
  • Produksi HBsAg dan Anti-HBsAg Untuk Pengembangan serta Komersialisasi Kit Diagnostik Hepatitis B Indonesia. Rispro-LPDP. Ketua. 2016-Present
  • Pengembangan “Dimer Based Screening System” untuk penapisan cepat kandidat antituberkulosis baru. P3MI-ITB. Ketua. 2017-2018
  • The Development of Intranasal Therapeutic and Preventive Hepatitis B Vaccine using Norovirus P Particle as Vaccine Delivery System. Riset Kerjasama Luar Negeri DIKTI. Ketua. 2017
  • Purification of P-particle and Riset Centre and development of intranasal therapeutic and preventive hepatitis B vaccine. Advance Science ITB. Ketua. 2015
  • Studi dimerisasi PhoR tuberculosis untuk pengembangan obat baru. Riset inovasi KK ITB. Ketua. 2015
  • Development and production of subunit hepatitis B vaccine in Indonesia Ristek-PT Bio Farma(PI): Konsorsium Nasional Vaksin Hepatitis B. Koordinator Tim ITB. 2012-2017
  • Riset Kerjasama Luar Negeri, 2017, Pengembangan Vaksin Hepatitis B Intranasal menggunakan P-Particle, kerjasama dengan Virginia Tech, US (Principal Investigator)
  • Rispro LPDP, 2016, Produksi HBsAg dan Anti-HBsAg Untuk Pengembangan serta Komersialisasi Kit Diagnostik Hepatitis B Indonesia (Principal Investigator)
  • National Vaccine Consortium in Hepatitis B Insentif Riset Sinas-Kementrian Riset-Teknologi, 2012-…… (Co-Researcher, ITB Coordinator) Development and production of Subunit Hepatitis B Vaccine in Indonesia
  • Riset Centre and Advance Science ITB. 2015. Purification of P-particle and development of intranasal therapeutic and preventive Hepatitis B vaccine.
  • Riset Inovasi KK ITB.2015. Studi dimerasisasi PhoR M.tuberculosis untuk pengembangan obat baru.
  • Riset Unggulan ITB.2015. Pengembangan humanized antibodi monoclonal anti-HBsAg
  • Riset Inovasi KK ITB.2014. Determination of 3-D conformation of Phor domain sensor of Mycobacterium tuberculosis for development of new anti tuberkular. 2014. Funded by Institut Teknologi Bandung
  • Cloning and crystallization of PhoR cytoplasmic domain from Mycobacterium tuberculosis to develop novel multitarget antitubercular drug. 2013. TWAS Grant
  • Pathogenesis and immunology of enteric virus. 2012. Fulbright Visiting Scholar 2012 : in Dr.Lijuan Yuan Laboratory, Virginia Tech, US.
  • Riset dan Inovasi KK ITB, 2012 (Princial Investigator) Production of Modified L-HBsAg in Plant as a Protective Hepatitis B Vaccine Antigen
  • Riset PP Pangan, Kesehatan dan Obat ITB, 2011 (Principle Investigator) Initiation of Hepatitis B Surface Antigen (HBsAg) Production based on Indonesian isolate in Pichia pastoris
  • Riset Hibah Kompetisi Strategis Nasional, DIKTI, 2009-2011 (Principle Investigator) Production of L-HBsAg in plant to solve National Health Problem
  • Riset Unggulan ITB, 2009 (Principle Investigator) Production of Hepatitis B surface antigen (HBsAg) and mutein G145R HBsAg in Pichia pastoris
  • Riset kompetitif LIPI- 2007-2011 (Co-Researcher) Development of Hepatitis B edible vaccine
  • Riset Desentralisasi DIKTI, 2012 (Principal Investigator) Purification and Crystalization of PhoR Sensor Domain Mycobacterium tuberculosis as a target of Novel Antitubercular
  • National Vaccine Consortium in Tuberkulosis, Insentif Riset Sinas-Kementrian Riset-Teknologi, 2012 (Co-Researcher, ITB Coordinator) Development of Prototype of Tuberculosis Vaccine
  • Indonesian Torray Science Foundation, 2009 (Co-researcher) Targetting PhoP-PhoR two component signal transduction to develop a novel high throughput screening system for searching new antibacterial against M . tuberculosis
  • Riset Internasional ITB, 2008, collaboration with School of Pharmacy ITB and University of Groningen, Netherlands (Co-Researcher) Molecular characterization of streptococcal adhesin to human fibronectin using Surface Plasmon Resonance
  • KNAW Mobility Program, collaboration with School of Pharmacy ITB and University of Groningen, Netherlands (Co-Researcher) Drugs development of Streptococcus Pyogenes
  • Joint Research Program Hibah Kompetisi B (PHK-B)-DIKTI, Kerjasama SITH-ITB dan Fakultas Kedokteran UK Maranatha : 2009 (Co-Researcher) Development of FCGamma RIII detection
  • Riset Hibah Kompetitif Strategis Nasional DIKTI, 2009 (Co-Researcher) Development of HCV diagnostic kit
  • Riset Insentif Kementrian Ristek dan Teknologi, 2007 (Co-Researcher) Microsateliate in Penaues Monodon
  • Riset Pembinaan Ilmu Kedokteran (Risbin-Iptekdok), Kerjasama dengan Universitas Hasanudin , 2007 (Konsultan) Overexpression of Cpn-1 as Tuberculosis vaccine candidate
  • Hibah Pekerti DIKTI, Kerjasama dengan Universitas Hasanudin , 2006 (Co-Researcher) VP 28 as White Spot Syndrome Virus vaccine candidate in shrimp
  • Riset Fakultas – ITB Kerjasama dengan Kelompok Keahlian Biokimia – ITB , 2006 (Coresearcher) Protein analysis of gene expressed in invation process of Salmonella typhi straind Indonesia
  • Riset Pembinaan Ilmu Kedokteran (Risbin-Iptekdok), Kerjasama dengan Universitas Hasanudin, 2006 (Consultant) Immune response variant against Anti-ESAT6 in M akasar
  • Intitation of collaboration with Dr. Claire Leuseur, National University of Singapore , 2005 Site directed mutagenesis of Cholera toxin B subunit to investigate cholera toxin assembly in vitro
  • Indonesian Torray Science Foundation, 2004 ( (Principal investigator) Study of D51 mutant of two component regulatory system of Vibrio cholerae
  • PhD Thesis, 2003 The Cpx two component regulatory system of Vibrio cholerae (Supervisor : Prof.T.R.Hirst, University of Bristol, UK)

Keanggotaan Organisasi

  • American Society of Virology. Virology. Member. 2017-Present
  • Society of Indonesian Microbiology, Bandung Branch Chairman Juni 2011-…
  • Society of Indonesian Microbiology, Bandung Branch Program Coordinator 2005-2011
  • Society of Indonesian Biochemistry and Molecular Biology, Bandung Branch Member 2011-…

Mata Kuliah

Undergraduate Courses

  • Basic molecular and cell biology, applied in molecular and cell biology, diagnostic microbiology
  • Microbial physiology (practical), microbial pathogenesis and immunology, project on microbial genetics
  • Virology, current issues in biotechnology
Tahun Nama Mata Kuliah
2024/2025 Aplikasi Omics Dalam Mikrobiologi
2024/2025 Virologi Molekuler
2024/2025 Vaksin dan Diagnostik
2024/2025 Patogenesis Mikroba
2024/2025 Biologi Sel Molekuler
2024/2025 Genetika dan Rekayasa Genetika Mikroba
2024/2025 Mikrobiologi Terapan
2024/2025 Teknologi Biokatalis dan Enzim
2024/2025 Infeksi dan Imunitas

Intelectual Property Rights (IPR)

  • Terdaftar dan Dipublikasi:PLASMID REKOMBINAN YANG BERFUNGSI SEBAGAI VEKTOR EKSPRESI UNTUK PRODUKSI BERLEBIH HEPATITIS B SURFACE ANTIGEN (HBsAg) DI HANSENULA POLYMORPHA. No Pendaftaran : P00201407051. 2014. Paten diajukan bersama  PT Biofarma (Persero) dan ITB.Biofarma : Neni Nurainy, Gilang Nadia, Vanny NaritaITB : Dessy Natalia, Ernawati A. Giri-Rachman (SITH/PP Biosains Bioteknologi ITB), Debbie Soefie Retnoningrum dan Fernita Puspasari
  • Terdaftar :VIRUS–LIKE PARTICLE PROTEIN SMALL HEPATITIS b SURFACE ANTIGEN (sHBsAg) UNTUK BAHAN BAKU VAKSIN HEPATITIS B DAN PROSES PRODUKSINYA DI SEL INANG Pichia pastoris.No Pendaftaran : p00201504908. 12 Agustus 2015Paten diajukan bersama  PT Biofarma (Persero) dan ITBBiofarma : Neni Nurainy, Gilang Nadia, Dicky MahardhikaITB : Ernawati A. Giri-Rachman (SITH/PP Biosains Bioteknologi ITB), Dessy Natalia, Debbie Soefie Retnoningrum, Elvi Restiawaty, Wardono Niloperbowo dan Fernita Puspasari

Honour, Awards, dan lain-lain

  • Satyalencana Karya Satya 10 Year
  • 57th ITB anniversary award to field of research
  • Sinas Research Incentive Award
  • Fulbright Visiting Scholar Program
X