Dr.rer.nat. I Dewa Made Kresna
Lecturer
Genetics and Molecular Biotechnology
School of Sciences and Technology
Institut teknologi bandung, Indonesia
dewa.kresna@itb.ac.id
SINTA | Google Scholar | Scopus | Wos
OVERVIEW
Dr.rer.nat. I Dewa Made Kresna, S.Pd., M.Si. The group explores bioactive natural bioactive products. The current research primarily focuses on the discovery and development of new antibiotics by genome mining, protein characterization, and biosynthetic pathway manipulation.
| Year | Institution | Program | Notes |
|---|---|---|---|
| 2013 | Universitas Negeri Manado, Indonesia | Chemistry Education | Bachelor’s Degree |
| 2016 | Institut Teknologi Bandung, Indonesia | Biochemistry | Master’s Degree |
| 2022 | Justus-Liebig-Universität Giessen, Germany | Biology/Biotechnology | Doctoral Degree |
| Year | Publications |
|---|---|
| 2021 | Kresna, I. D. M., Linares-Otoya, L., Milzarek, T., Duell, E. R., Mohseni, M. M., Mettal, U., König, G. M., Gulder, T. A. M., & Schäberle, T. F. (2021). In Vitro Characterization of 3-Chloro-4-Hydroxybenzoic Acid Building Block Formation in Ambigol Biosynthesis. Organic & Biomolecular Chemistry, 19(10), 2302–2311. https://doi.org/10.1039/d0ob02372h |
| 2021 | Wuisan, Z. G., Kresna, I. D. M., Böhringer, N., Lewis, K., & Schäberle, T. F. (2021). Optimization of Heterologous Darobactin A Expression and Identification of the Minimal Biosynthetic Gene Cluster. Metabolic Engineering, 66, 123–136. https://doi.org/10.1016/j.ymben.2021.04.007 |
| 2022 | Kresna, I. D. M., Wuisan, Z. G., & Schäberle, T. F. (2022). Production of Antimicrobial Compounds by Homologous and Heterologous Expression. Methods in Molecular Biology, 55–73. https://doi.org/10.1007/978-1-0716-2855-3_4 |
| 2022 | Kresna, I. D. M. Discovery and Development of Antibiotics by Genome Mining, Protein Characterization and Biosynthetic Pathway Manipulation. JLUpub, Dissertationen. https://doi.org/10.22029/jlupub-15691 |
| 2022 | Kresna, I. D. M., Wuisan, Z. G., Pohl, J., Mettal, U., Otoya, V. L., Gand, M., Marner, M., Otoya, L. L., Böhringer, N., Vilcinskas, A., & Schäberle, T. F. (2022). Genome-Mining-Guided Discovery and Characterization of the PKS-NRPS-Hybrid Polyoxyperuin Produced by a Marine-Derived Streptomycete. Journal of Natural Products, 85(4), 888–898. https://doi.org/10.1021/acs.jnatprod.1c01018 |
| 2022 | Nguyen, H., Kresna, I. D. M., Böhringer, N., Ruel, J., De La Mora, E., Kramer, J., Lewis, K., Nicolet, Y., Schäberle, T. F., & Yokoyama, K. (2022). Characterization of a Radical SAM Oxygenase for the Ether Crosslinking in Darobactin Biosynthesis. Journal of the American Chemical Society, 144(41), 18876–18886. https://doi.org/10.1021/jacs.2c05565 |
| 2023 | Marner, M., Kolberg, L., Horst, J., Böhringer, N., Hübner, J., Kresna, I. D. M., Liu, Y., Mettal, U., Wang, L., Meyer-Bühn, M., Mihajlovic, S., Kappler, M., Schäberle, T. F., & Von Both, U. (2023). Antimicrobial Activity of Ceftazidime-Avibactam, Ceftolozane-Tazobactam, Cefiderocol, and Novel Darobactin Analogs Against Multidrug-Resistant Pseudomonas aeruginosa Isolates from Pediatric and Adolescent Cystic Fibrosis Patients. Microbiology Spectrum, 11(1). https://doi.org/10.1128/spectrum.04437-22 |
| 2024 | Böhringer, N., Wuisan, Z. G., Marner, M., Kresna, I. D. M., Mettal, U., Schmitt, S., Reiter, S., Liu, Y., Brinkrolf, K., Rupp, O., Schwengers, O., Findeisen, J., Herold, S., Matt, U., & Schäberle, T. F. (2024). Nanoliter-Scale Selection of Optimized Bioengineered Peptide Antibiotics That Rescue Mice with Bacterial Lung Infection. bioRxiv (Cold Spring Harbor Laboratory). https://doi.org/10.1101/2024.05.30.596569 |
| Date | Title | Scheme | Role | Contract/Letter Number |
|---|---|---|---|---|
| 02.06.2025 | Genome Mining Mikroba Danau Halofil Gili Meno dan Ekspresi Lassopeptide sebagai Antibiotik Potensial | Penelitian Kemdiktisaintek Tahun 2025 | Member | Kementerian Pendidikan, Kebudayaan, Riset dan Teknologi [DRI.PN-14-47-2025]: 345/IT1.B07.1/SPP-DRI/V/2025 |
| 02.06.2025 | Eksplorasi dan Optimalisasi Terapi Rheumatoid Arthritis Berbasis Sel Punca Pulpa Gigi: Pendekatan Imunomodulator dan Personalisasi Spesifik Jenis Kelamin | Penelitian Kemdiktisaintek Tahun 2025 | Member | Kementerian Pendidikan, Kebudayaan, Riset dan Teknologi [DRI.PN-14-65-2025]: 363/IT1.B07.1/SPP-DRI/V/2025 |
| 03.05.2025 | Penambangan Genom Isolat TSI_13 Penghasil Anti-Mikroba yang Diisolasi dari Danau Gili Meno, Indonesia | PPMI SITH 2025 – Seed Funding untuk Penelitian Dosen Muda | PIC | ITB [SITH.PPMI-1-62-2025]: 42A/IT1.C11/SK-TA/2025 |
| 16.06.2025 | Penambangan Genom (Genome Mining) Antibiotik Baru dari Isolat Bakteri Aktif yang Diisolasi dari Hutan Cibolang, Jawa Barat, Indonesia | Revio Call | PIC | NSXX31U0 |
| 14.10.2025 | Atlas Single-Cell RNA Sequencing (SCRNA-Seq) Imunologi Malaria: Upaya Dekonstruksi Heterogenitas Respons Sel Imun PBMC Pasien Papua dan Jawa serta Eksplorasi Dental Pulp Stem Cells sebagai Terapi Inovatif | Penelitian dan Inovasi EQUITY 2025 | Member | LPDP, Kementerian Keuangan Republik Indonesia [DRI.PN-17-130-2025]: 8128/IT1.B07.1/TA.00/2025 |
| 23.02.2026 | Monitoring Terpadu Ekosistem Perairan Cirebon sebagai Dasar Ilmiah Ketahanan Pangan dan Adaptasi Perubahan Iklim di Tengah Ancaman Kenaikan Muka Air Laut dan Pembangunan Giant Sea Wall | Riset Peningkatan Kapasitas Peneliti ITB Tahun 2026 | Member | ITB [FITB.PN-6-138-2026]: 2235/IT1.B07.1/TA.00/2026 |
| 01.04.2026 | Eksplorasi dan Rekayasa Biosynthetic Gene Clusters (BGC) Mikroba Halofil Danau Gili Meno untuk Pengembangan Kandidat Antibiotik Baru | PPMI SITH ITB 2026 | Member | ITB: 47A/IT1.C11/SK-TA/2026 |
| Date | Title | Role | Contract/Letter Number |
|---|---|---|---|
| 2025 | Alih Teknologi Penyiapan Bahan Pangan Berbasis Tumbuhan di Lahan Secaba Rindam III Bihbul | Member | PPMI SITH |
| 07.07.2025 | Program Budidaya Buah Pisang dan Sayur untuk Mendukung Ketahanan Pangan di Bali | Member | ITB, Pengabdian Masyarakat Ketahanan Pangan Tahun 2025 [DPMK.PM-8-143-2025]: -/IT1.B07.5/TA.01/2025 |
| 07.07.2025 | Pembuatan Video Kegiatan Progam PM Makanan Bergizi | PIC | ITB, Pengabdian Masyarakat Ketahanan Pangan Tahun 2025 [DPMK.PM-8-145-2025]: -/IT1.B07.5/TA.01/2025 |
| 02.03.2026 | Integrasi Skrining Malaria–HIV–TBC dan Pendampingan Kepatuhan Obat Berbasis Komunitas di Jayapura, Papua untuk Memutus Siklus Kekambuhan Malaria | Member | ITB, Pengabdian Masyarakat Skema Bottom-Up Tahun 2026 [DPMK.PM-8-104-2026]: 1356/IT1.B07.5/TA.01/2026 |
| Year | Location | Program | Notes |
|---|---|---|---|
| 04.2026 | BRIN Cibinong | Workshop: Introduction to Single Cell Sequencing: Unlocking Cellular Biology in Suspension Cell Systems | Participant |
| 01.2026 | Online Webinar | Map out the future of human health with spatial biology (Xenium In Situ Webinar) | Participant |
| 09.2021 | Online | The 4th European Conference on Natural Products | Participant |
| 09.2020 | Bad Nauheim, Germany | MegaSyn Symposium on Megasynthases | Poster Presenter |
| 10.2019 | Giessen, Germany | de.NBI Environmental Genomics Workshop | Participant |
| 09.2019 | Jena, Germany | International VAAM workshop 2019 on Biology of Microorganisms Producing Natural Products | Poster Presenter |
| 08.2018 | Frankfurt, Germany | VAAM workshop on The Biology of Bacteria Producing Natural Products | Poster Presenter |
| 11.2016 | Bandung, Indonesia | The 6th International Conference on Mathematics and Natural Sciences – On the Road Towards Sustainable Development | Poster Presenter |
| 11.2015 | Institut Teknologi Bandung, Indonesia | The Fifth Gruber-Soedigdo Lecture – Biocatalyst for Food, Energy, and Medical Applications, Bandung | Participant |
| Date | Institution | Position |
|---|---|---|
| 01.2026 – present | SITH, ITB | Administrative Coordinator for the Expert/Academic Group |
| 01.2026 – present | SITH, ITB | Post Graduate Student Advisor, SITH |
| 01.2025 – present | SITH, ITB | SITH Website Update Team |
| 09.2024 – present | Institut Teknologi Bandung | University Lecture |
| 04.2022 – 04.2024 | Remofarm GmbH & Co. KG, Germany | Biotechnologist |
| 06.2021 – 03.2022 | Justus Liebig University of Giessen, Germany | Research Assistant |
| 01.2015 – 12.2015 | Chemistry Department, FMIPA, ITB | Laboratory Teaching Assistant |
| Year | Organization’s Name | Role/Position |
|---|---|---|
| 2025 – present | American Society for Microbiology | Global Outreach – Contributing Member |
| Academic year | Course name |
|---|---|
| 2024/2025 | Molecular Biology |
| 2024/2025 | Genetics and Molecular Biology Practicum |
| 2024/2025 | Cell and Molecular Biology Project |
| 2024/2025 | Genetics and Molecular Biology |
| 2024/2025 | Marine Biotechnology |
| 2025/2026 | Molecular Biology K01 |
| 2025/2026 | Genetics (Cirebon) |
| 2025/2026 | Genetics Practicum (Cirebon Class K03) |
| 2025/2026 | Genetics and Molecular Biology |
| 2025/2026 | Marine Molecular Biology |
| 2025/2026 | Genetics and Molecular Biology Practicum |
| Year | Type | Title | Organizer | Location | Category (Institutional/National/International) |
|---|---|---|---|---|---|
| 2025 | Task Force | SITH Official Website Update Team | SITH, ITB | Institutional | |
| 2017-2021 | Scholarship | DAAD | The German Government | Germany | International |
| 2015 | Scholarship | Thesis Scholarship | DIKTI | Bandung, Indonesia | Institutional |
| 2015 | Organizing Committee | “The Fifth Gruber-Soedigdo Lecture – Biocatalyst for Food, Energy, and Medical Applications” | Chemistry, FMIPA, Institut Teknologi Bandung, Indonesia | Bandung, Indonesia | National |