Once thought to only play a role in the process of endogenous molecular signaling, plant small-RNAs are now gaining popularity as an agent in cross-kingdom communication. Similarly, the role of self-DNA in extracellular signaling is getting more attention to control growth of the its producing cells. In this article, Dr. Karlia Meitha and colleagues propose the potential application of smallRNAs and extracellular self DNA for developing green pesticides. This could be a promising alternative if we are to provide food for the future global population without further damaging the environment.
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Article Citation:
Meitha, K., Esyanti, RR., Iriawati, I., Hanisia, RH., Rohyani, R. 2021. Green pesticide: Tapping to the promising roles of plant secreted small RNAs and responses towards extracellular DNA. Non-coding RNA Research. 6(1):42-50.
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Full paper is published in Non-coding RNA Research: https://doi.org/10.1016/j.ncrna.2021.02.001

Image (first page):
The proposed mechanisms of entry triggered cellular signaling cascade and phenotypic response of extracellular DNA or RNA exposure to plants (Meitha et al. 2021)
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Profile of Dr. Karlia Meitha:
https://sith.itb.ac.id/en/karlia-meitha-ph-d/