
KARLIA MEITHA, Ph.d.
Assistant Professor
Genetics and Molecular Biotechnology
School of Sciences and Technology
Bandung Institut of Technology
Email : karliameitha@itb.ac.id
SINTA | Google Scholar | Scopus
OVERVIEW
Karlia Meitha, Ph.D. primarily focuses in Genetics an Molecular Biotechnology, specifically in the research of genome editing; small-RNAs for biocontrol; epigenetics; and high-antioxidant production in crops
Bachelor’s Degree
- Bandung Institute of Technology, Indonesia (2006).
Master’s Degree
- Bandung Institute of Technology, Indonesia (2010).
Doctoral Degree
- Universiy of Western Australia, Australia (2017).
Year | Institution | Position |
Dec 2017 – 2020 | The Research Foundation of Indonesia Biogeography and Biodiversity Director, Bandung, Indonesia | |
Feb 2017 – 2020 | Bali International Research Centre for Banana Secretary Bali, Indonesia | |
Jan – Dec 2015 Jan – Dec 2014 | The Association of Indonesian Postgraduate Students and Scholars in Australia | Vice President Treasurer Perth, Australia |
Jan 2018 – Present | Institut Teknologi Bandung Bandung, Indonesia | Jan 2018 – Present |
Oct 2016 – Dec 2017 | Institut Teknologi Bandung Bandung, Indonesia | Academic Assistant and Postdoctoral Fellow |
Aug – Nov 2014 | The University of Western Australia | Demonstrator for laboratory practice |
Jun 2013 – Sep 2013 | Leeds University Leeds, UK Visiting researcher |
- Wicaksono, A., Meitha, K., Wan, K., Isa, M. N. M., Parikesit, A. A., & Molina, J. (2025). Hairpin in a haystack: In silico identification and characterization of plant-conserved microRNA in Rafflesiaceae. Open Life Sciences, 20(1). https://doi.org/10.1515/biol-2022-1033
- Septiani, P., Pramesti, Y., Ghildan, M. et al. RNAi-based biocontrol for crops: a revised expectation for a non-recent technology. Planta 261, 44 (2025). https://doi.org/10.1007/s00425-025-04625-0
- Hermawaty, D., Putri, M. A., Prabhandiya, S., Dwivany, F. M., & Meitha, K. (2025). Epigenetic regulation of banana fruit ripening: global and specific DNA methylation profile, and characterization of DNA methylation-related genes. Cogent Food & Agriculture, 11(1). https://doi.org/10.1080/23311932.2024.2448267
- Fauziah, T., Esyanti, R. R., Meitha, K., Iriawati, N., Hermawaty, D., & Wijayanti, G. a. I. F. (2024). Cell cycle arrest via DNA damage response (DDR) pathway induced by extracellular Self-DNA (ESDNA) application in rice root. Plant Physiology and Biochemistry, 219, 109370. https://doi.org/10.1016/j.plaphy.2024.109370
- Dwivany, F. M., Fauziah, T., Yamamoto, K., Novianti, C., Perwira, K. P. C., Rizanti, M., Radjasa, S. K., Hakim, F. S., Salim, A. S. P., Putri, R. R., Wicaksono, A., Sumardi, D., Putri, S. P., Fukusaki, E., Meitha, K., & Nugrahapraja, H. (2024). Chitosan coating to delay the ripening process in banana: a transcriptomics study. Horticulture Environment and Biotechnology, 66(1), 123–136. https://doi.org/10.1007/s13580-024-00642-2
- Manuhara, Y. S. W., Sugiarso, D., Fajar, A. P., Niam, K., Aziz, R. T., Yudha, A. W., Clement, C., Daryono, B. S., Miftahudin, M., Meitha, K., Nurhayati, A. P. D., & Wibowo, A. T. (2024). Optimizing Growth of Melon (Cucumis melo L. cv. Madesta) in Nutrient Film Technique and Drip Irrigation Hydroponics with Varied Substrates. Pertanika Journal of Tropical Agricultural Science, 47(4), 1191–1204. https://doi.org/10.47836/pjtas.47.4.09
- Negara, H. a. S. M. P., Esyanti, R. R., Iriawati, I., Signorelli, S., Kirana, R., & Meitha, K. (2024). Enhancing genetic modification in recalcitrant plants: An investigation in chili (<i>Capsicum annuum</i>) through the optimized tape sandwich protoplast isolation and polyethylene glycol-mediated transfection. Plant Biotechnology, 41(4), 459–464. https://doi.org/10.5511/plantbiotechnology.24.0613a
- Meitha, K., Chen, P. Y., Chang, C., Lin, Z. C., Hsu, T. W., Gojobori, T., & Chiang, T. Y. (2024). Is an invasive species a notorious invader or carbon sequencer?. Ecological Genetics and Genomics, 100279.
- Hermawaty, D., Meitha, K., & Esyanti, R. R. (2024). The Potential of Methylation Sensitive Amplification Polymorphism (MSAP) Technique to Study Global DNA Methylation Changes in Plants: Basic Principles and Perspective. Reviews in Agricultural Science, 12, 93-110.
- Septiani, P., Pramesti, Y., Ningsih, D. U., Pancaningtyas, S., & Meitha, K. (2024). Identification of self-and pathogen-targeted miRNAs from resistant and susceptible Theobroma cacao variety to black pod disease. Scientific Reports, 14(1), 3272.
- Tham, J., Patisenah, A., Tjia, T. O. S., Signorelli, S., Taufik, I., & Meitha, K. (2023). sgRNA design and in vitro nucleolytic analysis of the Cas9‐RNP complex for transgene‐free genome editing of the eIF4E1 gene from Capsicum an‐nuum L. Indonesian Journal of Biotechnology, 28(4), 238-247.
- Meitha, K., Hanisia, R. H., Signorelli, S., Fauziah, T., Iriawati, and Esyanti, R. R. (2023) Extracellular DNA of Fusarium oxysporum sp. cubense as a priming agent for inducing the resistance of banana plantlets. Agronomy. 13(2:441). https://doi.org/10.3390/agronomy13020441
- Wiprayoga, I., Meitha, K., and Dwivany, F.M. (2023) In Silico Characterization of Lycopene Beta Cyclase (LCYB) and Lycopene Epsilon Cyclase (LCYE) Genes from DH-Pahang (Musa acuminata, A Genome) and DH-PKW (Musa balbisiana, B Genome). Journal of Tropical Lofe Sciences. 13(1). https://doi.org/10.11594/jtls.13.01.09
- Tjia, T. O. S., Meitha, K., Septiani, P., Awaludin, R., and Sumardi, D. (2023) Extracellular self-DNA induces local inhibition of growth, regulates production of reactive oxygen species, and gene expression in rice roots. 67, 9-18. DOI: 10.32615/bp.2022.037
- Meitha, K., Pramesti, Y., Signorelli, S., and Kriswantoro, J.A. (2022) Postharvest chitosan application maintains the quality of spinach through suppression of bacterial growth and elicitation. Horticulture, Environment, and Biotechnology. 63(2), 217-227. https://doi.org/10.1007/s13580-021-00397-0
- Suhandono, S., Kusuma, S. H., Meitha, K. (2021) Characterization and Production of Rhamnolipid Biosurfactant in Recombinant Escherichia coli Using Autoinduction Medium and Palm Oil Mill Effluent. Brazilian Archives of Biology and Technology. https://doi.org/10.1590/1678-4324-2021200301
- Meitha, K., Esyanti, R. R., and Hanisia, R. H. (2021) Green pesticide: Tapping to the promising roles of plant secreted small RNAs and responses towards extracellular DNA. Non-coding RNA Research. 6(1). 42-50. https://doi.org/10.1016/j.ncrna.2021.02.001
- Setiabudi, E., Meitha, K., and Dwivany, F. M. (2021) In silico characterization and comparison of the fruit ripening related beta‐amylase (BAM) gene family in banana genome A and B. Indonesian Journal of Biotechnology. 26(4). https://doi.org/10.22146/ijbiotech.65142
- Kusuma, S. H., Meitha, K., Suhandono, S. (2021) Characterization of Di-Rhamnolipid Biosurfactant in Recombinant Escherichia coli. Key Engineering Materials.https://doi.org/10.4028/www.scientific.net/KEM.874.107
- Dwivany, F. M., Sukriandi, N., Meitha, K., Brotosudarmo, T. H. P. (2021) In silico Characterization of the Structure of Genes and Proteins related to β-carotene Degradation in Musa acuminata ‘DHPahang’ and Musa balbisiana’Pisang Klutuk Wulung’. Pertanika Journal of Tropical Agricultural Science. 44(2). DOI: https://doi.org/10.47836/pjtas.44.2.10
- Nugrahapraja, H. N., Dwivany, F. M., Meitha, K., Kuswati, Esyanti, R. R. (2021) Chitosan improving Growth in Chili (Capsicum annuum L.) Plants and acting through Distinct Gene Regulation between Cultivars. Research Journal of Biotechnology. 16(2)
- K. Pramesti, Y., Suhandono, S. (2020) Reactive oxygen species and antioxidants in postharvest vegetables and fruits. International journal of food science. https://doi.org/10.1155/2020/8817778
- Meitha, K., Fatmawati, I., Dwivany, F.M., Sutanto, A., Pratama, S.N., Nugrahapraja, H., and Wikantika, K. (2020) Phylogenetic analysis of 23 accessions of Indonesian banana cultivars based on Internal Transcribed Spacer 2 (ITS2) region. Indonesian Journal of Biotechnology. 25(1). doi: 10.22146/ijbiotech.49506
- Aziz, M.A., Esyanti, R.R., Meitha, K., Dwivany, F.M., and Chotimah, H.H. (2020) Chitosan suppresses the expression level of WRKY17 on red chili (Capsicum annuum) plant under drought stress. Indonesian Journal of Biotechnology. 25(1). doi: 10.22146/ijbiotech.55016
- Dwivany, F. M., Ramadhan, M. R., Lim, C., Sutanto, A., Nugrahapraja, H., Wikantika, K., Pratama, S. N., Meitha, K., Pratiwi, A. S. (2020). Bali Bananas (Musa spp. L.) Genetic Relationship Based on Internal Transcribed Spacer 2 (ITS-2). Pertanika Journal of Tropical Agricultural Science. 43(4)
- Esyanti, R.E., Dwivany, F. M., Mahani, S., Nugrahapraja, H. & Meitha, K. (2019) Foliar application of chitosan enhances growth and modulates expression of defense genes in chilli pepper (Capsicum annuum L.). Australian Journal of Crop Sciences. 13(01). doi: 10.21475/ajcs.19.13.01.p1169
- Meitha, K., Agudelo-Romero, P., Signorelli, S., Considine, J., Foyer, C. & Considine, M. (2018) Developmental Control of Hypoxia During Bud Burst in Grapevine. Plant, Cell, and Environment. doi:10.1111/pce.13141
- Signorelli, S., Agudelo-Romero, P., Meitha, K., Foyer, C. H., & Considine, M. J. (2018) Roles for Light, Energy, and Oxygen in the Fate of Quiescent Axillary Buds. Plant Physiology. doi: 10.1104/pp.17.01479
- Rai, I N., Dwivany, F. M., Sutanto, A., Meitha, K., Sukewijaya, I M., and Ustriyana, I N. G. (2018) Biodiversity of Bali Banana (Musaceae) and its Usefulness. Hayati Journal of Biosciences. 25 (2). doi: 10.4308/hjb.25.2.47
- Hidayat, T., Kelana, H.W., Ismanto, D.I.A., and Meitha, K. (2018) Survey on Ethnobotanic Value of Banana (Musa spp; Musaceae) in Bali Province, Indonesia. Hayati Journal of Biosciences. 25 (1). doi:10.4308/hjb/25.1.31
- Shaw, D. S., Meitha, K., Considine, M. J., & Foyer, C. H. (2017). Mitochondrial Respiration and Oxygen Tension. In K. Jagadis Gupta (Ed.), Plant Respiration and Internal Oxygen: Methods and Protocols (pp. 97-113). New York, NY: Springer New York. https://doi.org/10.1007/978-1-4939-7292-0_11
- Meitha, K. & Considine, M. (2017) Regulation of Oxygen and Reactive Oxygen Species During Budburst. Wine and Viticulture Journal. 32:4. (pp. 42-45)
- Meitha, K. (2016). Promotor Gen: Tombol On/Off Ekspresi Gen yang Penting Bagi Kelangsungan Hidup Organisme. In Ketut Wikantika (Ed.), Bunga Rampai Forum Peneliti Muda Indonesia (pp. 9-14). Bandung: Penerbit ITB. ISBN: 978-602-7861-52-7
- Meitha, K., Konnerup, D., Colmer, T. D., Considine, J. A., Foyer, C. H., & Considine, M. J. (2015). Spatio-temporal relief from hypoxia and production of reactive oxygen species during bud burst in grapevine (Vitis vinifera). Annals of Botany (Reactive Oxygen and Nitrogen Species). doi:10.1093/aob/mcv123
HAKI
- SEDIAAN MEDIA TRANSPORT VIRUS INAKTIF UNTUK MENYIMPAN VIRUS TERINAKTIVASI SECARA AMAN DAN METODE PEMBUATANNYA Nomor Permohonan : P00202214780
- PLASMID REKOMBINAN DAN SEL INANG Escherichia coli REKOMBINAN PENGHASIL DIRHAMNOLIPID SERTA METODE PRODUKSI DIRHAMNOLIPID DENGAN KOMPOSISI MEDIA EKSPRESI YANG OPTIMUM MENGGUNAKAN PLASMID DAN SEL INANG TERSEBUT DALAM MENGHASILKAN VARIAN DIRHAMNOLIPID SEBAGAI BIOSURFAKTAN Nomor Permohonan : P00202001556
Year | Activity | Leader | Personnel |
2023 | MOLECULAR PHYLOGENETIC ANALYSIS AND DNA BARCODE [SITH.PPMI-2-07-2023] | Dadang Sumardi | Fenny Martha Dwivany; Adi Pancoro; Sony Suhandono; Husna Nugrahapraja; Azzania Fibriani; Ernawati Arifin Giri-rachman; Karlia Meitha; Popi Septiani; |
2024 | MENGGALI POTENSI SUMBERDAYA GENETIK PADI LOKAL MELALUI PEMULIAAN PARTISIPATIF DI KECAMATAN TANJUNGSARI KABUPATEN SUMEDANG [SITH.PPMI-2-11-2024] | Popi Septiani | Dadang Sumardi; Husna Nugrahapraja; Azzania Fibriani; Ernawati Arifin Giri-rachman; Sony Suhandono; Adi Pancoro; Karlia Meitha; Fenny Martha Dwivany; |
funding
Year | Research Title |
2020 | Pengadaan Virus Transport Media (VTM) Untuk Mendukung Pengujian Terhadap Virus SARS-Cov2 |
2020 | Rekayasa Kultivasi Microgreens dalam Sistem Urban Farming Untuk Meningkatkan Kandungan Antioksidan |
2021 | Optimasi Pembuatan Virus Transport Media (VTM)-Inactivated Sebagai Produk Kemandirian Bangsa yang Mampu Berkontribusi pada Penanganan Penyebaran Covid-19 |
2021 | Pengembangan Cabai (Capsicum annuum) Tahan Hama Potyvirus melalui Modifikasi Gen eIF4E menggunakan Metode Edit Genom CRISPR-Cas9 |
2022 | Analisis Mekanisme “Cell Cycle Arrest” Akibat Perlakuan Self- Dan Non Self Extracelullar Dna” Pada Kecambah Padi |
2022 | Identifikasi MiRNA Theobroma Cacao Sebagai Kandidat Biopestisida Phytophthora Palmivora |
2022 | Pengembangan Sistem Sintesis Protein Cas9 dengan Solubilitas Tinggi untuk Edit Genom Berbasis CRISPR-Cas9 BebasTransgenik |
2023 | Analisis Global Metilasi DNA untuk Pengembangan Manajemen Pascapanen |
2023 | Analisis Transkriptomik dan Metabolomik dalam Biosintesis Karotenoid dan Toleransi Cekaman Abiotik pada Genotipe Melon Indonesia Hasil Aplikasi Potassium |
2023 | Edit Genom Daerah Cetakan miRNA di Cabai untuk Meningkatkan Ketahanan terhadap Phytophthora capsica |
2023 | International Student Conference (ISC) |
2023 | Molecular Phylogenetic Analysis and DNA Barcode (PM) |
2023 | Studi Biodiversitas Molekuler Mikroba Danau Halofilik Gili Meno Lombok |
2024 | STUDI BIODIVERSITAS DANAU GILI MENO – LOMBOK DENGAN PENDEKATAN GENOMIK |
2024 | Potensi Carbon-Nanodots sebagai komponen bahan lokal untuk mensubtitusi koloid emas pada tes diagnostik SARS-COV-2 |
2024 | PRODUKSI PROTEIN SPIDROIN REKOMBINAN UNTUK REKAYASA JARINGAN KARTILAGO [SITH.PPMI-1-11-2024] |
2024 | SKRINING KETAHANAN TERHADAP CEKAMAN KEKERINGAN PADA PADI LOKAL |
Professional membership
- International Society for Horticultural Science, 2022 – present
- Asian Federation of Biotechnology (Indonesia Chapter), 2022 – present
- Indonesian Biotechnology Program Association, 2020 – present
- Society of Experimental Biology, London, United Kingdom, 2013 – present
Undergraduate Courses
- Genetics; Syntetic Biology; Fundamentals for Protein Engineering;
- Cellular and Molecular Biology; Microbial Genetics and Genetic Engineering
Postgraduate Courses
- Advanced Molecular Genetics; Biotechnology of Postharvest; Plant Stress and Biotechnology
- Research Design, Bioethics, and Patent; Biotechnology Research and Seminar; Thesis and Final Defense
Year | Courses |
2024/2025 | Praktikum Genetika |
2024/2025 | Biologi Molekuler |
2024/2025 | Biologi Molekuler |
2024/2025 | Genetika dan Biologi Molekuler |
2024/2025 | Praktikum Genetika dan Biologi Molekuler |
2024/2025 | Penulisan dan seminar proposal |
2024/2025 | Penelitian Magister I |
2024/2025 | Penelitian Magister II dan Seminar A |
2024/2025 | Sidang Magister |
2024/2025 | Bioteknologi Ketahanan Tumbuhan |
2024/2025 | Tren dalam Bioteknologi I |
2024/2025 | Metodologi Penelitian |
2024/2025 | Dasar Rekayasa Protein |
2024/2025 | Proyek Biologi Sel Molekuler dan Genetika Mikroba |
2024/2025 | Genetika dan Biologi Molekuler |
2024/2025 | Praktikum Genetika dan Biologi Molekuler |
2024/2025 | Tren dalam Bioteknologi I |
2024/2025 | Metodologi Penelitian |
2024/2025 | Penulisan dan seminar proposal |
2024/2025 | Penelitian Magister I |
2024/2025 | Nanoteknologi untuk Bioteknologi |
2024/2025 | Penelitian Magister II dan Seminar A |
2024/2025 | Penulisan Tesis |
2024/2025 | Sidang Magister |
Awards
L’Oreal Unesco for Women in Science |
2023 |
Joint Seminar and Focus Group Discussion “Toward Sustainable Agriculture: The Role of Plant Breeding and Biotechnology” |
2023 |
Inisiasi kolaborasi pendidikan dan riset |
2023 |
Research visit to Dr. Keiji Nishida laboratory at Kobe University, Japan |
Nov 2022 – Feb 2023
|
Granted by the Rector of ITB at the 63rd Dies Natalis |
Feb 2022 |
The 5th International Biology Conference, Biology Department, ITS – Indonesia |
October 2020 |
To attend annual main meeting in Prague, Czech. |
Jun – Jul 2015 |
Research visit to Prof. Christine Foyer laboratory at Leeds University. |
Jun – Sep 2013 |
The University of Western Australia. |
Jun 2012 – Jul 2016 |
Udayana University, Bali – Indonesia. |
Sep 2009 |
Grants
1. Riset Kolaboratif antar KK- ITB
Edit Genome of MiRNA Template Regions in Chili to Increase Resistance to Phytophthora capsici |
Mar – Nov 2023
|
2. Riset Peningkatan Kapasitas KK – ITB
Global Analysis of DNA Methylation for Postharvest Management Development |
Mar – Nov 2023
|
3. Riset Unggulan – ITB
Development of Highly Soluble Cas9 Synthesis System for Transgenic Free CRISPR-Cas9 Genome Engineering |
Feb – Nov 2022
|
4. PPMI KK GBM – SITH ITB
Identification of Theobroma cacao miRNA as Biopesticide Candidate for Phytophthora palmivora |
Feb – Nov 2022 |
5. Riset Unggulan – ITB
Development of Potyvirus Resistant Chili (Capsicum annuum) through Modification of the eIF4E Gene using the CRISPR-Cas9 Genome Editing Method |
Feb – Nov 2021 |
6. Riset Inovasi LPiK – ITB
Optimization of the manufacture of Inactivated Virus Transport Media (VTM) |
Feb – Nov 2021 |
7. Research Grant (PT. Rekacipta Inovasi – ITB)
Recovery Rate Determination of Activated Virus Transport Medium |
Feb – Nov 2021 |
8. Research Grant (LPiK – ITB)
The preparation of viral transport media for local detetion center in Bandung |
May – Oct 2020 |
9. Riset peningkatan kapasitas – ITB
Improving antioxidant contents in microgreens by combination of red and blue light 10. Research Grant P3MI – ITB Effect of Chitosan Coating on the Postharvest Quality and Regulation of Gene Expression Related to ROS (Reactive Oxygen Species) od Spinach (Spinacia oleracea) |
Feb – Nov 2020
Feb – Nov 2019 |
The Research Foundation of Indonesia Biogeography and Biodiversity Director, Bandung, Indonesia Dec 2017 – 2020 |
Plan, lead, and review organisational development strategies with the board of directors |
Bali International Research Centre for Banana SecretaryBali, Indonesia Feb 2017 – 2020 |
Facilitate the communication between two main universities involved in the research, ITB and Udayana University; Managing research activities. |
The Association of Indonesian Postgraduate Students and Scholars in Australia Vice President Treasurer Perth, Australia Jan – Dec 2015 Jan – Dec 2014 |
Collaborated with other community organizations in Perth to create friendship events in sports and women in leadership.Promoted and managed fund-raising projects.Informed future Indonesian students about education systems and life in Australia. |
Bandung Institut of Technology Lecturer and Researcher Bandung, Indonesia Jan 2018 – Present |
· Facilitate students to grasp the knowledge in Biology topics and related research skills
· Conduct research in the field of plant biomolecular and its application |
Institut Teknologi Bandung Bandung, Indonesia Academic Assistant and Postdoctoral Fellow Oct 2016 – Dec 2017 |
· Conducted biomolecular research in the topics of banana diversity.
· Assisted the curriculum evaluation process and preparation of new curriculum documents for Microbiology |
The University of Western Australia Demonstrator for laboratory practice Perth, Australia Aug – Nov 2014 |
· Guided undergraduate students to perform essential physiology and molecular experiments.
· Helped the students to understand crucial concepts underlying the experiments. |
Leeds University Leeds, UK Visiting researcher Jun 2013 – Sep 2013 |
· Observed the localization of reactive oxygen species in grape bud tissues by using histological method.
· Examined techniques for mitochondria extraction and oxygen consumption rate measurements. |