We are glad to share a new study from Dr. Anggraini Barlian’s team who reported the potential of silk spidroin from Argiope appensa spider web on directing chondrogenic differentiation of human Wharton’s jelly Mesenchymal Stem Cells (hWJ MSCs). It is useful for the development of bio based material scaffold in cartilage tissue engineering, suggesting a new alternative for cell based therapy in cartilage damage repair system.
Barlian, A., Judawisastra, H., Ridwan, A., Wahyuni, AR, Lingga ME. (2020). Chondrogenic differentiation of Wharton’s Jelly mesenchymal stem cells on silk spidroin-fibroin mix scaffold supplemented with L-ascorbic acid and platelet rich plasma. Sci Rep 10, 19449 .
Full paper is published in Scientific Report: https://doi.org/10.1038/s41598-020-76466-8
Image (first page):
Immunocytochemistry of collagen type II in hWJ MSCs grown on silk fibroinspidroin mix Scaffold
Profile of Dr. Anggraini Barlian: