Dr. rer. nat. I Dewa M. Kresna
Lecturer
School of Sciences and Technology
Bandung Institut of Technology
Expertise Group: Genetics and Molecular Biotechnology
Email: dewa.kresna@itb.ac.id
OVERVIEW
Dr. rer. nat. I Dewa M. Kresna explores bioactive natural products produced by microbes for lead drugs. His current research primarily focuses on the discovery and development of new antibiotics by genome mining, protein characterization, and biosynthetic pathway manipulation.
| 2022 | Justus-Liebig-Universität Giessen (Biology/Biotechnology) |
| 2016 | Institut Teknologi Bandung (Biochemistry) |
| 2013 | Universitas Negeri Manado (Chemistry Education) |
- 2024 Böhringer, N., Wuisan, Z. G., Marner, M., Kresna, I D. M., Mettal, U., Schmitt, S., Reiter, S., Liu, Y., Brinkrolf, K., Rupp, O., Schwengers, O., Findeisen, J., Herold, S., Matt, U., Schäberle, T. F. bioRxiv 2024.05.30.596569. doi: 10.1101/2024.05.30.59656
- 2023 Marner, M., Kolberg, L., Horst, J., Böhringer, N., Hübner, J., Kresna, I D. M., Liu, Y., Mettal, U., Wang, L., Meyer-Bühn, M., Mihajlovic, S., Kappler, M., Schäberle, T. F., von Both, U. Antimicrobial Activity of Ceftazidime- Avibactam, Ceftolozane-Tazobactam, Cefiderocol, and Novel Darobactin Analogs against Multidrug-Resistant Pseudomonas aeruginosa Isolates from Pediatric and Adolescent Cystic Fibrosis Patients. Microbiology Spectrum, 11, e04437-22. doi: 10.1128/spectrum.04437-22
- 2022 Kresna, I D. M., Wuisan, Z. G., Schäberle, T. F. Production of Antimicrobial Compounds by Homologous and Heterologous Expression. In: Sass, P. (eds) Antibiotics. Methods in Molecular Biology, vol 2601. Humana, New York, NY. Doi: 10.1007/978-1-0716-2855-3_4
- 2022 Nguyen, H., Kresna, I D. M., Böhringer, N., Ruel, J., de la Mora, E., Kramer, J.-C., Lewis, K., Nicolet, Y., Schäberle, T. F., Yokoyama, K. Journal of the American Chemical Society, 144, 41, 18876–18886. doi: 10.1021/jacs.2c05565
- 2022 Kresna, I D. M. Discovery and development of antibiotics by genome mining, protein characterization and biosynthetic pathway manipulation. JLUpub, Dissertationen. doi: 10.22029/jlupub-15691
- 2022 Kresna, I D. M., Wuisan, Z. G., Pohl, J.-M., Mettal, U., Otoya, V. L., Gand, M., Marner, M., Otoya, L. L., Böhringer, N., Vilcinskas, A., Schäberle, T. F. Genome-Mining-Guided Discovery and Characterization of the PKS-NRPS- Hybrid Polyoxyperuin Produced by a Marine-Derived Streptomycete. Journal of Natural Products, 85, 4, 888–898. doi: 10.1021/acs.jnatprod.1c01018
- 2021 Wuisan, Z. G., Kresna, I D. M., Böhringer, N., Lewis, K., Schäberle, T. F. Optimization of heterologous Darobactin A expression and identification of the minimal biosynthetic gene cluster. Metabolic Engineering, 66, 123-136. doi: 10.1016/j.ymben.2021.04.007
- 2021 Kresna, I D. M., Linares-Otoya, L., Milzarek, T., Duell, E. R., Mohseni, M. M., Mettal, U., König, G. M., Gulder, T. A. M., Schäberle, T. F. In vitro characterization of 3-chloro-4-hydroxybenzoic acid building block formation in ambigol biosynthesis. Organic & Biomolecular Chemistry, 19, 2302-2311. doi: 10.1039/D0OB02372H
| 2017 | Awarded by DAAD for Ph.D. scholarship |
| 2015 | Awarded by DIKTI for final thesis scholarship |
| 2022 – 2024 | Biotechnologist at Remofarm GmbH & Co. KG, Germany. In vivo screening of natural antimelanotic compounds, probiotics in hatchery, and training as a hatchery manager for developing “organic food products”. |
| 2021 – 2022 | Research Assistant at Justus Liebig University of Giessen, Germany. |
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